Drug Discovery Letdown

Brought to you by MISFIT www.misfitwearables.com/references DRUG DISCOVERY UP M building to a let DOWN 1 3 6. 7 8 Drug Discovery: Preclinical Investigational Clinical Trials Clinical Trials Trials Clinical Trials Phase 3: New Drug Green Medical Application light! Submitted New Drug Application: can help?" toxic?" "Will you let us test this on humans?" Phase 1: "Is it safe?" Phase 2: Marketing "What "Is it "Does it & "Does it work?" Manufacturing "Let's make this!" After all that effort, only 1 in 4 of us take it properly! help?" to FDA Potential Drugs Invested 3 in 4 of us are non-adherant ($Million) in one or more ways 100 200 300 400 500 600 700 800 900 Developing Time (years) Non-adhering patients contribute to an estimated $300 Billion in additional healthcare costs! 1 4 7 8. 9. 10 11 12 13 14 15 = 100 volunteers Testing Lower Bound Upper Bound