Birth Defects related to Clomid

Clomid linked to many Birth Defects: The Centers for Disease Control (CDC) issued a warning after an analysis of data from the National Birth Defects Prevention Study linked Clomid with higher rates of many birth defects. Clomid The study was published in Human Reproduction in November 2010 and involved women who used Clomid and gave birth from 1997-2005. Anencephaly (2.3x risk): Baby is born missing large parts of its brain and skull Clomid (CLOMIPHENE CITRATE) is used to treat infertility in women. It works by stimulating an increase in the amount of hormones that support the growth and release of a mature egg (ovulation). This medication is not recommended for women whose ovaries no longer make eggs properly (primary pituitary or ovarian failure). Dandy-Walker malformation (4.4x risk): Abnormal development of the cerebellum (part of the brain that controls movement) Muscular ventricular septal defect (4.9x risk): "Hole in the heart" between two lower chambers Common Side Effects: Septal heart defects (1.6x risk): "Hole in the heart" defects upset stomach bloating abdominal/pelvic fullness flushing ("hot flashes") breast tenderness headache or dizziness Coarctation of the aorta (1.8x risk): Narrowing of the aorta that causes high blood pressure and heart damage Cloacal exstrophy (5.4x risk): Abdominal organs are exposed, genitals are split, and anus may be sealed Craniosynostosis (1.9x risk): Premature fusion of skull bones resulting in decreased brain size and Serious Side Effects: abnormally-shaped head abnormal vaginal bleeding mental/mood changes vision problems/changes serious allergic reaction Other Clomid Birth Defects Birth defects which may be associated with Clomid by this and other studies include: Down syndrome Hernias Spina bifida Mental retardation Hip malformations Conjoined twins Kidney defects Cerebral palsy Oral cleft defects Still birth Omphalocele Sources: http://www.clomidbirthdefects.org/ http://www.webmd.com/ http://humrep.oxfordjournals.org/content/early/2010/ 11/26/humrep.deq313.abstract