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World MS Day

Living with Multiple Sclerosis (MS) MS is an inflammatory disease that damages the nerves and affects the transfer of messages from the central nervous system to the rest of the body. It is progressively disabling and often leaves people with limited mobility. FINLAND NORWAY 6,000 7,500 SWEDEN 13,000 MS is more DENMARK common than you think 7.2 7,500 UK IRELAND 85,000 POLAND 10,000 NETHERLANDS 16,000 50,000 BELGIUM MS affects more | 9,000 GERMANY CZECH REPUBLIC than 600,000 people in Europe 3 122,000 16,000 SWITZERLAND 9,000 FRANCE SLOVAKIA 100,000 > PEOPLE 80,000 8,400 AUSTRIA 8,000 ITALY 54,000 PORTUGAL 50,000 - 100,000 PEOPLE 5,000 SPAIN 40,000 < 50,000 PEOPLE What are the symptoms of MS? 4 MS management & quality of life ranking across countries 3 This is not always related to a country's wealth and there is large room for improvement BALANCE AND COORDINATION PROBLEMS 92% 1 GERMANY 2 ICELAND 3 SWEDEN 4 AUSTRIA 5 NORWAY 6 ITALY VII. VISUAL PROBLEMS O O074% VIII. VII. VII 7 SLOVENIA VIII VIII VIII 8 DENMARK 9 BELGIUM 10 UK 11 NETHERLANDS 12 FRANCE 13 FINLAND 14 SWITZERLAND 15 IRELAND 16 LUXEMBOURG 17 CZECH R 18 RUSSIA 19 SLOVAKIA 20 PORTUGAL 21 MALTA 22 CROATIA 23 GREECE 24 SPAIN 25 HUNGARY 26 ROMANIA 27 ESTONIA 28 LITHUANIA 29 SERBIA 30 POLAND 31 BULGARIA 32 BOSNIA-H 33 BELARUS ABNORMAL SPEECH O 68% VIIII VIII FATIGUE O 96% SPASTICITY 82% MUSCLE PAIN O 81% ALTERED SENSATIONS SUCH AS TINGLING AND "PINS AND NEEDLES' 88% UP TO 80%. OF PEOPLE WITH MS SUFFER FROM MODERATE OR ┼×EVERE SPASTICITY (RIGIDITY AND SPASMS) 5 Spasticity is one of the more neglected MS symptoms What are the consequences of spasticity for MS patients? 6 Over 50% of people with moderate to severe MS do not receive treatment to control their spasticity 7 66% 40% 51% Restricted movements Pain Poor sleep 1. Multiple Sclerosis International Federation. www.atlasofms.org, Last S Databa accessed 03/05/2012 2. The Norwegian Association for MS-patients. http://www.ms.no. Last accessed on 17 May 2012 3. European Multiple Sclerosis Platform. MS Barometer 2011. www.EMSP.org Last accessed 08.05.12 4. Hemmett Let al. What drives quality of life in multiple sclerosis?QJ Med 2004; 97:671-676 5. Rizzo MA, Hadjimichael OC, Preiningerova J, et al. Prevalence and treatment of spasticity reported by 70% 70% 17% multiple sclerosis patients. Mult Scler 2004;10:589-595. 6. Oreja-Guevara C, Gonzalez D, Vila Cet al. Multiple sclerosis spasticity in Spain: the 6E patients' survey. Poster. Presented at: 5th Joint triennial Congress of the European and Americas Committees for Treatment and Research in Multiple Sclerosis (Amsterdam). Multiple Sclerosis Journal 2011;17:580 Pass water several times in the night Difficulty walking Require further help with washing and dressing 7. Flachenecker P, Henze T, Hengsbach M, et al. Spasticity in Multiple Sclerosis - a cross-sectional survey in Germany. Accepted at RIMS 2012, May 2012. E Almirall For further information on Multiple Sclerosis please visit www.LifeandMS.com GMBSATO295

World MS Day

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Learn about people living with Multiple Sclerosis and show your support for World MS Day by spreading the word.

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