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The Science of CBD & Hemp

он но THE SCIENCE OF CBD Ultimate Beginner's Guide THE BASICS Hemp and marijuana are two varieties of the same plant - cannabis. So just like oranges and lemons are both citrus plants, hemp and marijuana are both cannabis plants. HEMP MARIJUANA HEMP EXTRACT VS • Contains CBD • Made from flowers + leaves Very high in CBD Very low in THC (<0.3%) Not psychoactive Legal nationwide Very high in THC Very low in CBD Psychoactive Legal in some states VS НЕМP OIL • Contains no CBD • Made from seeds THE AMAZING HEMP PLANT The hemp plant has over 50,000 different known uses. Human Use of the hemp plant was fully legalized in the U.S. with the 2018 Farm Bill. Since then, use dates back to 6,000 B.C. CBD extracts have been available nationwide. STALKS SEEDS FIBER HURDS OIL SEEDCAKE NUTS NLATION ROOTS LEAVES + FLOWERS BUDNC CANNABINOIDS 101 Cannabinoids are natural compounds produced by many plants and animals, including humans. Yup, even your body is making cannabinoids all the time. Over 120 cannabinoids exist in hemp. There are two types of cannabinoids: Phytocannabinoids are found in plants (CBD is one of them). Endocannabinoids are naturally produced by our bodies. Benefits CBD Cannahidiel • Helps you relax and reduce stress • Improves sleep and rest • Increases overall well-being CBDA CBG Benefits Cennabigerol • May help to fight inflammation • Has anti-bacterial properties • Has positive effects on stomach health CBGA Non-Psychoactive CBC Benefits Cannabichramene • Being studied as an anti-inflammatory • May have positive effects on mood • Shows potential for brain health CBCA Benefits THC Tetrahydrocannabinel • Being studied for dozens of medical uses • Reduces feelings of stress and anxiety • Could help with PTSD and trauma THCA THCV Benefits Tetrahydrocannabivarin • May be beneficial for weight loss • Could reduce anxiety • Shows promise to be anti-inflammatory THCVA Psychoactive CBN Benefits Cannobinel • Could stimulate healthy appetite • May be anti-bacterial and neuro-protective • Could be a potent anti-inflammatory agent CBNA TERPENES 101 Terpenes are natural compounds found in all plants. They are what make fruits, vegetables, and other plants taste and smell the way they do. Picture the sweet smell of an strawberry, or the fresh scent of mint. That's terpenes doing their thing! Hemp plants produce many natural terpenes. Let's take a look at some of them: Bisabolol Borneol Camphene Caryophyllene Delta 3 Carene Eucalyptol Geraniol Humulene hapetien erts sperties Limonene Linalool Myrcene Pinene Phytol Terpinolene Trans-nerolidol Valencene far erties haies barti heties FLAVONOIDS 101 Flavonoids are a group of so-called phytonutrients (natural plant chemicals) found in almost all fruits and vegetables. They are responsible for the vivid colors and amazing aroma of all plants, including fruits, vegetables, and yes, hemp. Some very beneficial flavonoids can only be found in hemp plants! They're called cannaflavins. Aplgenin Anthocyanins Beta-sitosterol Cannflavin A Cannflavin B Isovitexin Prepertes Camman Camman s Cemman Vs Kaempferol Luteolin Orientin Quercetin Silymarin Vitexin Cemmen Ves Comman M THE ENTOURAGE EFFECT Taking cannabinoids, terpenes, and flavonoids together in their natural combination increases their individual benefits. In short, they interact and work much better together. That's the Entourage Effect. That's the reason you should look for CBD products that include all three: CANNABINOIDS TERPENES +. FLAVONOIDS YOUR "ECS" The Endocannabinoid System (ECS) is an important system in your body that regulates your well-being and daily experience. Your ECS is filled with tiny receptors (in your brain and nervous system) that naturally interact with cannabinoids to regulate your mood, energy, sleep, and more. These receptors use your own cannabinoids (Endocannabinoids) and those made by plants (Phytocannabinoids). The Endocannabinoid System CBD, CBN and THC fit like a lock and key into existing receptors. These receptors are part of the endocannabinoid system which impact physiological processes affecting pain modulation, and appetite plus anti-inflammatory effects and other immune system responses. The endocannabinoid system comprises two types of receptors. CB1 and CB2, which serve distinct functions in animal health and well-being. Presynaptic Tetrahydrocannabinol Cannabinoid receptor CB1 receptors are primarily found in Receptors CB1 the brain and central Lipid precursons nervous system, and to a lesser extent in other tissues CB2 receptors are mostly in the pereheral organs especially cells associated with the immune system CB2 Neurotransmitters Cannabinoids Postsynaptic CB1 RECEPTORS ARE LOCATED CB1 AND CB2 RECEPTORS ARE IN CELLS OF THE : LOCATED IN CELLS OF THE : Brain/CNS/Spinal cord (CB1) Cortical regions (CB1): (neocortex, pyriform cortex, hippocampus, amygdala) Eye (CB1 and CB2) retinal pigment epithelial/RPE cells Heart (CB1 and CB2) Cerebellum (CB1) Stomach (CBI and CB2) Brainstem (CB1): Basal ganglia (CB1): globus pallidus, substantia nigra pars, reticulata Olfactory bulb (CB1) Pancreas (CB1 and CB2) Digestive tract (CB1 and CB2) Bone (CB1 and CB2) Thalamus (CB1) Non-CB1 and non-CB2 are located in cells of the: Blood vessels: epirthelial cells of arterial Hypothalamus (endocrine-grain link CB1) Pituitar (CB1 Thyroid (endocrine gland (CB1) blood cessels (non-CB1 and non-CB2) Upper airways (of mammals CB1) Liver (CBI Kupffer cells (acrophage immune cells), hepatocytes (liver cell. hepatic stellate cells (fat storage cell Adrenals (endocrine gland CB1) CB2 receptors are located in cells of the: Lymphatic and immune system Spleen (CB2) Thymus (CB2) Ovaries (gonads and endcrine gland CB1) Uterus (myometrium C81) Tonsis (CB2) Blood (CB2) lymphocytes Prostate (CB1): epithelial and smooth muscle cells Testes (gonads and endocrine gland CB1): leydig cells; sperm cells Non-immune cell CB2 receptors are found in the Skin keratinocytes Endocannabinoids Phytocannabinoids • AEA • CBD • CBG CBC Anandamide Cannabidiol Cannabigerol Cannabichromene • 2-AG • CBN • THCV THC 2-Arachidonoylglyceral Cannahinol Tetrahydrocannabivarin Tetrahydrocannabinol CBD EXTRACTION METHODS To get hemp extract, dried hemp is processed. The quality of the CBD and how many natural compounds are still present in the final extract depend greatly on the production method. OLIVE OIL I ETHANOL II • Hemp is added to olive oil • It's then heated for several hours • Hemp is soaked in alcohol • Alcohol is evaporated • Cheap, but uses ethanol • Perishable with short shelf life SUPER-CRITICAL CO2 II SUB-CRITICAL CO2 III • Natural C02 gas used, with no traces • Natural C02 gas used, with no traces • Low temperature and low pressure • High temperature and high pressure • Great extraction but heated a lot • Great extraction and closer to raw ::: POPULAR WAYS TO TAKE CBD There are lots of different ways to take CBD. The main difference is the bioavailbility of the CBD and other cannabinoids. What's bioavailability? That's how well your body can actually absorb the product. In short, the higher the bioavailability the better, because you get more of what you paid for. SPRAYS CAPSULES EDIBLES Spray in mouth Bioavailability: I Take orally Chew and swallow Bioavailability: I Bioavailability: I TOPICALS VAPES TINCTURES Apply to skin Smoke (health risks) Drops under tongue Bioavailability:I Bioavailability: II Bioavailability: II CBD's MANY USES Scientists are studying hundreds of potential benefits of CBD. But because CBD has only been legal since 2018, promising research is still in the early stages. * STRESS ANXIETY O MOOD ) EXERCISE RECOVERY SLEEP CHOOSING A CBD PRODUCT There are a lot of different CBD brands out there. Some are great, many have questionable quality, and some are outright dishonest. CBD oil is not a product where you should skimp on quality. You deserve a hig-quality product that's effective and safe. USDA Third-Party Uses Only Certified Organic Lab Tests Flowers Look for CBD that's 100% Most companies use stalks, which is cheap but not premium. Lab tests should show USDA certified organic quality, purity, and strength. and non-GMO. Grown & All-Natural Transparent Labels Made in the USA Ingredients Carrier oil, hemp extract, natural flavor, terpenes. Look for brands that grow, make, and ship in the USA. Check the amount of actual CBD you get per bottle and serving. That should be all. Sustainable Money-Back Customer Practices Guarantee Support You deserve to have your Being sustainable and environmentally friendly is the way to go. Look for risk-free trials with free shipping and questions answered transparently. free returns. FAIR USE & SOURCES Fair Use Statement: Feel free to share this infographic with your readers for any noncommercial use. Make sure you include a link back to this page or to www.getjupiter.com so that our team gets credit. jupiter Organic CBD Drops © 2020 Jupiter Brands Inc. All rights reserved. Learn more: www.getjupiter.com https://www.health.harvard.edu/blog/cannabidiol-cbd-what-we-know-and-what-we- dont-2018082414476 https://www.sciencenews.org/article/cbd-product-boom-science-research-hemp-marijuana https://www.nature.com/articles/d41586-019-02524-5 https://sciencebasedmedicine.org/cbd-oil-the-new-miracle-cure/ https://www.nytimes.com/2019/10/16/style/self-care/cbd-oil-benefits.html https://www.webmd.com/pain-management/news/20180507/cbd-oil-all-the-rage-but-is-it-safe- effective#1 https://adai.uw.edu/marijuana/factsheets/cannabinoids.htm https://www.webmd.com/a-to-z-guides/qa/what-are-the-medical-benefits-of-cannabinoids https://nccih.nih.gov/health/marijuana-cannabinoids https://www.sciencedirect.com/science/article/pii/SO168945219301190 https://www.sclabs.com/terpenes/ https://www.healthline.com/health/what-are-flavonoids-everything-you-need-to-know https://untamedscience.com/blog/review-and-understanding-cbd-manufacturing-process/ https://www.sciencedirect.com/science/article/abs/pii/S2212982018304220 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412000/ https://www.uclahealth.org/cannabis/human-endocannabinoid-system https://www.healthline.com/health/endocannabinoid-system https://untamedscience.com/blog/review-and-understanding-cbd-manufacturing-process/ https://sips.cals.cornell.edu/extension-outreach/industrial-hemp/ https://www.cell.com/trends/plant-science/pdf/S1360-1385(17)30177-2.pdf https://www.newsweek.com/2019/09/06/cbd-oil-miracle-drug-science-1456629.html https://www.cell.com/trends/plant-science/pdf/S1360-1385(17)30177-2.pdf https://www.sciencedirect.com/science/article/pii/S1525505016305856 https://www.getjupiter.com/cbd-beginners-guide/ https://www.getjupiter.com/education/

The Science of CBD & Hemp

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Discover everything you need to know about CBD and hemp with this illustrated beginner’s guide. Learn about CBD, hemp, and cannabinoids. This illustrated beginner’s guide explains the amazing use...

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