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OUTBREAK Because a virus doesn't care about state lines or national borders, it can wipe out millions and span multiple continents rapidly. Here is a look at the infectious diseases the world has battled throughout history. Weight Loss Chills Red Eyes Diarrhea Fever Headache Fatigue Bleeding Dehydration Key: What is a Pandemic? Derived from the Greek word pandemos meaning "pertaining to all people," a pandemic is a widespread disease that affects humans over a wide geographic area. Deadliest Pandemics in History Bubo PANDEMIC DEATH TOLL Sore Throat YEAR B Cough Vomiting Seizures 25+ million 25 million A bubo is an abnormal swelling of the lymph nodes. PLAGUE of JUSTINIAN 541 - 750 Skin Discoloration, Lesions HIV / AIDS 1981 - TODAY Rash Nausea MEASLES 7th Century BC - 1963 Honorable Mentions SPANISH FLU Although the following viruses do not have a figure for total amount of lives claimed, they continue to terrorize various areas around the world. SMALLPOX 200 million 10,000 BC - 1979 1918 - 1919 MALARIA 1600 - Today Common Symptoms Chills, Headache, Fever, Jaundice, Muscle Pain, Nausea, Vomiting, Seizures 50-100 million 300+ million Death Toll According to the World Health Organization's 2010 "World Malaria Report," an estimated 781,000 people are killed by the virus every year. Bigpox? In terms of an estimated death toll, smallpox is the deadliest pandemic in history. The highly contagious, rash-inducing infection has killed more than 500 million people. Some believe that 90 percent of the native population of the New World was wiped out by the disease. TUBERCULOSIS 700 BC - Today Common Symptoms BLACK DEATH Chest Pain, Cough, Fever, Chills, Fatigue THIRD 1340 - 1771 PANDEMIC 12 million Death Toll 1855 There are almost 2 million tuberculosis-related deaths worldwide every year. 75 million YELLOW FEVER 16th Century - Today Common Symptoms Ring Around the Rosie, a Pocket Full of Plague HONG ΤΥΡHUS CHOLERA 4 million 3 million KONG FLU 1968 - 1969 1 million Bleeding, Fever, Nausea, Vomiting. Delirium, Seizures, Jaundice 430 BC - TODAY 1817 - TODAY Legend says the Black Death plague inspired the children's rhyme "Ring Around The Rosy," which alluded to the rash-like rings and ashes of the deceased victims. Death Toll Worldwide, 30,000 deaths are caused by the infection every year. Sources: Mayo Clinic // Centers for Disease Control and Prevention // World Health Organization // New York Times // National Center for Biotechnology Information A COLLABORATION BETWEEN GOOD AND COLUMN FIVE


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From the Black Death to the measles, rapidly spreading diseases have taken a toll on humanity for centuries. Here's a look at the biggest and deadliest pandemics ever.




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