Down's Syndrome - A Chromosomal disorder

Down's Syndrome A Chromosomal Abnormality Down syndrome is a genetic disorder caused when abnormal cell division results in extra genetic material from chromosome 21. A normal human being has 22 pairs of Autosome and 1 Pair of Sex chromosome. Sperm Egg 4 1 XXX X X X X ------ 6 7 8 9 10 11 6 7 8 9 10 11 12 15 16 17 18 13 14 15 16 17 18 19 20 21 XIY 19 20 A Sperm contains 22 Autosome & 1 sex chromosome (either X or Y) An Egg contains 22 Autosome & sex chromosome X. Fertilization Down's Syndrome Baby Normal Baby XX XX XX XX XX XX XX XX XX XX XX XX XX XX XX XX XX 6 10 11 12 10 11 12 M M M XX XX XX M MM XX XX XX 13 14 15 16 17 18 13 16 17 18 19 20 XXIXY 19 20 21 22 XXIXY Down Syndrome baby contains 22 pairs of Autosome with 1 extra 21st chromosome. And 1 pair of sex chromosome (either XX or XY) Normal baby contains 22 pairs of Autosome and 1 pair of sex chromosome (either XX or XY) OccupationalTherapy 0T. com Source- https://en.wikipedia.org/wiki/Down_syndrome http://www.mayoclinic.org/diseases-conditions/down-syndrome DOC