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Complete 2015-16 Induced Pluripotent Stem Cell (iPSC) Industry Report

BioInformant Stem Cell Market Data :: What's hot today? IPSC News Today March 14, 2015 www.BioInformant.com The Business of Commercializing Induced Pluripotent Stem Cells (IPSCS) 50 40 30 20 10 2006 2007 2008 2009 2010 2011 2012 2013 2014 Year Number of Companies Offering iPSC Research Products, by Year When IPSCS were discovered in 2006, there were only two companies selling IPSC research products. This number increased to seven by 2007 and then began increasing more substantially. A year-by-year breakdown is shown above to identify the rate of new new market entrants and the current level of market competition for IPSC-specific research products. Market Penetration Among Stem Cell Researchers Clinical Trials Investigating ¡PSCS 30 20 10 Year # of Clinical Trials Investigating IPSCS Currently, there are 26 clinical studies involving the creation and evaluation of IPSC lines for clinical purposes. None of these studies involve transplant of iPSCs into humans (cellular therapy). [Visit ClinicalTrials.gov a list of current trials.] 22% of all stem cell researchers now self-report having used IPSCS within a research project. Major Advances in Commercialization of IPSCS AUGUST 2014: A historic patent dispute occurs between a group called "BioGatekeeper" and Drs. Yamanaka and Takahashi, who hold a U.S. patent claiming a method for creating IPSCS. If successful in canceling this patent, it could spur incredible innovation by allowing for lower cost creation of IPSC products, technologies, and therapies. AUGUST 2013: 1st time in which clinical research involving transplant of IPSCS into humans was initiated. Masayo Takahashi at RIKEN Center in Japan investigates safety of IPSC-derived cell sheets in patients with macular degeneration. JULY 2013: Cellular Dynamics International (CDI) went public with a offering that raised $43 million dollars, securing the company's position as the global leader in producing human IPSCS in industrial quantities. MARCH 2013: Celullar Dynamics International and Coriell Institute for Medical Research receive multi- million dollars grants from the California Institute for Regenerative Medicine (CIRM) for creation of IPSC lines from 3,000 healthy and diseased donors. It will create the world's largest human IPSC bank. The past two years have seen major advances in IPSC clinical research applications, production and differentiation technologies, biobanking, and more. ### Need to make smarter decisions, faster? Claim the "Complete 2015-16 Induced Pluripotent Stem Cell Industry Renort " by visiting: httn://www bioinformant com/product/comnlete-2015: powered by Piktochart I I make information beautiful # of Companies # of Trials

Complete 2015-16 Induced Pluripotent Stem Cell (iPSC) Industry Report

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Traditionally, scientists have worked with both embryonic and adult stem cells for research tools, as well as for cellular therapy. For more details : http://goo.gl/UUe1lH

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