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The Burden of multidrug-resistant tuberculosis (MDR TB)

Enter Ende The burden of MDR TB Alt Tuberculosis (TB) 187 is a serious and sometimes lethal infectious bacterial disease which most commonly affects the lungs. It is usually caused by Mycobacterium tuberculosis people in the EU are diagnosed with TB every day MDR TB Multidrug-resistant tuberculosis Patients with MDR TB do not respond to standard treatment (isoniazid and rifampicin) TB cases decreased 5% One untreated over the last 5 years Notification rate per 100 000 population person with TB can infect 16.6 10-15 other individuals per year 15.8 15.0 Around 14.3 13.5 1 500 cases are reported in the EU every year 2008 2009 2010 2011 2012 Drug resistance is a man-made phenomenon caused by: - Poor quality drugs - Unfinished treatment - Inadequate use of drugs MDR TB treatment causes substantial side effects like vomiting, deafness, blindness, depression and fatigue To treat TB it takes at least To treat MDR TB it takes at least 2015 2014 February NT WTSSMT WTP February 6. 18 sMTWTHslsrwEESlSMTWTEA seTASOlas4ST 23456T sas 23021 months months and 4 different drugs May WTESS MT WTF 1234 6 with on average TWTFS MTWTFslsMTWTF 8 drugs 1234 17346 1020 21 2021 Bill August September KIwrEslsMTWTFS 12345 sMEWTF Costs for treatment of multidrug-resistant TB are 20212 17 21 2 2 2 2 22 2 Europe fails to treat MDR TB 27 2 5х higher than for TB INovember November December IsurwT slaMTWTES wr SMTWTFSIS HTWTFS 123466 ason121314leTES ID11 12 0 12 30 Average cost per MDR TB case in the EU, 2012: MDR TB TB 13% 33 000 € Diel Ret al., Costs of tuberculosis disease in the European Union: a systematic 77% analysis and cost calculation. 34% 57% Eur Respir ). 2014:43(2):554-65. Treatment successful not successful unknown Only 1 in 3 patients with MDR TB is treated successfully XDR TB Only 25% of all patients with extensively Extensive drug resistance drug-resistant TB XDR TB is resistant to even more drugs than MDR TB and therefore extremely difficult to treat finish treatment successfully ecoc Data from the Tuberculosis Surveillance and Monitoring in Europe 2014, ECDC/WHO Europe, Stockholm, 2014

The Burden of multidrug-resistant tuberculosis (MDR TB)

shared by arnehaeger on Mar 25
ECDC Infographic for World TB day - 24 March 2014. Tuberculosis and multidrug-resistant tuberculosis.




Arne Haeger


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