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Autism Spectrum Disorder

AUTISM SPECTRUM DISORDER 1in 88 children age 3 to 17 are diagnosed with autism each year ttttt BOYS are 4 times more likely than girls to have autism 10 to 17 % growth annually Autism is the fastest-growing developmental disorder • DIAGNOSIS Disturbance in social interaction Language deficits Little or no eye contact Autism Spectrum Disorder (ASD) is comprised of an umbrella of disorders with varying degree of expression of above mentioned triad symptoms. Pervasive Aspergers Syndrome Autistic Disorder Developmental Disorder Not Otherwise Specified (PDD-NOS) Significant language delays. Impairment in social interaction and communiation. Restricted repetitive and stereotyped pattern of behavior, interest, and activity. No delay in language and cognitive development. Difficulties in social Symptoms are similar to autistic disorder. However, all criteria for interaction. Development of restricted and repetitive patterns of behavior, interest, and activity. autistic disorders are not met due to late age onset. Diagnostic and Statistical Manual of Mental Disorders DSM-5 will be released in May 2013 Autism Spectrum Disorder As of May 2013, previous diagnostic classification of Autistic spectrum disorders, - Aspergers Syndrome - Autistic disroder - Pervasive Developmental Disorder Not Otherwise Specified (PPD-NOS) will be replaced by one umbrella term "Autism Spectrum Disorder (ASD)." Environmental Genetic Factor X00000 Protective Factor Factor ASD RISK Current "Experimental Approaches" to determining genetic etiology for Autism Spectrum Disorder (ASD) Define an individual gene that encode proteins, which may contribute Analyze large number of individuals with ASD due to heterogeneity of the disorder the disorder >> Determine influence of Determine biological implication of genetic variation variations i.e. genetic etiology, environment factors on disorder Translation of genetic findings to biological models of ASD Reference: Geschwind DH. Advances in autism. Annu Rev Med. 2009,60:367-80. doi:10.1146/ Levitt P, Campbel| DB. The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders. J Clin Invest. 2009Apr;119(4):747-54. doi: 10.1172/JCI37934 illustration by Jooyeun Lee

Autism Spectrum Disorder

shared by J.L on May 16
Autism Spectrum Disorder is composed of an umbrella of disorders with varying degree of expression.


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