CAR T-Cell Immunotherapy

A cancer patient's immune system (T-cells) fails to recognise malignant cells 2 Autolus engineers the T-cells to express Chimeric Antigen Receptors (CARS) A viral vector is used to transfer a modifying gene into the T-cells The engineered T-cells express CARS T-cells extracted and activated MALIGNANT CELL Engineered T-cells are administered back to patient The CAR recognises targets on the surface of the malignant cell Engineered CAR T-cells destroy the malignant cells MALIGNANT CELL T 3 Engineered CAR T-cells recognise and destroy malignant cells