Prodynorphin

PRODYNORPHIN Prodynorphin, also known as is an opioid polypeptide hormone Proenkephalin B involved with chemical signal transduction and cell communication. PRODYNORPHIN is a basic building-block of endorphins, the chemical messengers in the brain. It is heavily involved in the anticipation and experience of pain and the formation of deep emotional bonds, and that are also critical in learning and memory. The gene for prodynorphin is expressed in the endometrium and the striatum, and its gene map locus is 20pter-p12 The gene is thought to influence perception, as well as susceptibility to drug dependence, and is expressed more readily in human beings than in other primates. Evolutionary implications Asian Most populations of Homo sapiens have two copies of the gene sequence for prodynorphin, whereas East Africans Middle Easterners Europeans tend to have three repetitions. The extent of regulatory gene disparities for prodynorphin, between human and primates, has gained the attention of scientists. Most Humans have multiple copies of the regulatory gene sequence for prodynorphin, which is virtually identical among all primates, whereas other primates have only a single copy. Blue Sky Issued by Peptide