Preimplantation Genetic Diagnosis/Preimplantation Genetic Screening

PGD/PGS What is PGD/PGS? Preimplantation Genetic Diagnosis Preimplantation Genetic Screening The screening of genetic diseases or chromosomal abnormalities in a dividing embryo prior to a woman conceiving. The PGD/PGS Process Several cells are biopsied from day-5 blastocysts which contain about 100 cells All 23 sets of XV XY XY XY XY XY chromosomes are XY XY XY XY XỲ XY XY. XY XY XY XY XY XY analyzed through Array CGH (comparative XY XY genomic hybridization) The embryos are then vitrified (cryopreserved) In a subsequent FET (Frozen Embryo Transfer) cycle, healthy embryos are transferred !E Indications 1 Family balancing/gender 2 Autosomal recessive disorders, such as... selection Cystic fibrosis Sickle-cell disease Tay-Sachs disease 3 Autosomal dominant disorders, such as X-linked recessive disorders, such as Neurofibromatosis Osteogenesis imperfecta Hemophilia A and B Duchene muscular dystrophy 5 For couples with recurrent pregnancy losses 6 Avoid having a child with Down's syndrome INFOGRAPHIC PROVIDED BY: www.ivf-dallas.com Dallas IVE SOURCE: http://www.dallasivf.com/ivf-dallas-tx/preimplantation- diagnosis.html