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People Powered Research

23andMe spit! People Powered Research Anyone can be a research participant. You don't need to have a specific disease or condition to make a meaningful contribution to research. Gathering millions of people to be active research participants could change the face of genetics research and improve the way we study diseases and develop new treatments - all from the DNA in your saliva. 23andMe's new people powered model for research has led to the discovery of more than 350 new genetic associations and our scientists have published their findings in 32 peer-reviewed studies. Here are a few examples of the number of people it takes to power meaningful genetic research studies. # of Research Participants Examples of what the scientific community discovered Examples of what 23andMe discovered* A 2008 study identified two genes associated with hair color and skin pigmentation. 23andMe published our first peer-reviewed study in 2010 identifying genetic associations for 22 common traits, including photic sneeze reflex. 2K - 5K 13 new genetic variants, likely involved in the immune system, In 2012, 23andMe identified 7 genetic associations with breast size that also influence breast were associated with celiac 5K - 20K disease in a 2010 study. cancer risk. In a study of multiple sclerosis, researchers identified 29 new 23andMe successfully replicated 180 genetic associations for common diseases including type 2 diabetes and prostate cancer, 20K - 50K genetic associations and shed light on the cellular pathways involved in the disorder. and identified new associations for nearsightedness, rosacea and stretch marks. A 2013 publication revealed 11 new genetic variants that increase the risk of Alzheimer's disease. 23andMe identified 35 genetic associations with motion sickness, many near genes involved in balance and eye and ear development. 50K - 100K A study of migraines identified 12 genetic associations, implicating pathways that regulate brain activity. In 2014, 23andMe contributed to a study of Parkinson's disease, which identified 26 genetic associations. 100K+ .this kind of research might lead to new insights for common and widely studied conditions. Researchers can run the largest genome-wide association studies to 1 million date... Imagine, with over 1 million research participants... researchers will have the data they need to identify rare genetic superheroes - individuals whose genetics indicate they should have a disease, when they don't. Genetic superheroes could hold the key to understanding and treating some of the world's most common and devastating diseases. Change the face of scientific discovery. #PowerOf1Million 23andMe.com *23andMe has genotyped more than one million customers. 80% of our customers have consented to participate in 23andMe research, and all published research papers stem from data collected from consented research participants. 23andMe research is conducted under accredited Institutional Review Board (IRB) approved protocols. Sources • National Human Genome Research Institute (NHGRI) GWAS catalog: https://www.genome.gov/26525384 • You can review 23andMe's published papers at: https://www.23andme.com/for/scientists/

People Powered Research

shared by 23andMe on Jul 13
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You don't need to have a specific disease or condition to make a meaningful contribution to research. Gathering millions of people to be active research participants could change the face of genetics ...

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